Ovarian Tumors: Clinicopathological Analysis

Background: Ovarian tumors are one of the main tumors affecting female at different age group with different histopathological types and broad clinical outcomes. Histologically, ovarian tumors are calcified into three main subtypes, surface epithelial tumors, germ cell tumors and sex cord tumors, each type then calcified as benign, borderline or malignant. The etiology, age relation, risk factors and clinical outcome for these tumors are differ according to their histological types. This study describes the distribution of ovarian tumors considering the age, the laterality and the histologic types in a selected group of patients. Materials and methods: A retrospective study including total number of 76 ovarian tumor was done. The specimens were collected from a private histopathology laboratory in Benghazi during the period from January 2019 to December 2020. The specimens were classified according to the newest WHO classification into epithelial tumors, germ cell tumors, sex cord?stromal tumors, and others. The lesions then were classified according to age, laterality and frequencies. The data were computed and analyzed. Results: The total number of specimens in this study was 76. most of the affected patients were between 21-40 years old (30%). the most commonly seen tumor was epithelial tumor (51%) followed by germ cell tumors (28%), sex cord stromal tumor (16%) and others (5%). the study concluded that the benign tumors form 72%, borderline tumors form 13% and the malignant tumors form 14%, the most common benign tumor in this study was serous cyst adenoma 20%, whereas the most common malignant one was serous cyst adenocarcinoma 9%. Regarding laterality, 50 were unilateral (66%) and 26 were bi-laterality (34%). Conclusion: In this study, the samples were classified according to WHO classification, majority of the tumors were epithelial and germ cell tumors. Most of cases were benign epithelial tumors. The most common type of epithelial and germ cell tumor was serous cystadenoma and teratoma, respectively, and the most commonly affected age group was 21 to 40 years old. The least common age group was 61 to 70 years old. Unilateral tumors were more frequently than bilateral tumors.