In-Vitro Anti-Histaminic Activity and Qualitative Biochemical Analysis of Seenthil Chooranam - A Siddha Herbo Animal Formulation

Background: Allergic diseases (Eg: Asthma, Allergic rhinitis, etc) are now classified as the fourth common global disease burden by the World Health Organization. The prevalence of allergic disease like Asthma has risen in the recent years. In recent years safe and effective management of diseases through plant resources has received much attention. Many plant medicines are used for their Anti histaminic and anti inflammatory properties. Histaminic plays a major role in the pathogenesis of asthma. Seenthil chooranam is a herbo animal drug used for the treatment of Eraippu (Bronchial asthma), Eelai (Tuberculosis), Kasam (Cough). Objective: The main objective of this study is to evaluate the anti-histaminic activity and the bio chemical activity of seenthil Chooranam. Methodology: Seenthil chooranam and its usage has mentioned in Agathiyar Paripooranam 400. The present study was undertaken to evaluate anti-histaminic activity of Seenthil chooranam (SC) by using isolated chick ileum preparation. In isolated chick ileum preparation, concentration response curve of histaminic in absence and in presence of SC was plotted. SC showed significant decrease in contraction induced by histaminic in isolated chick ileum preparation. These results show the anti-histaminic activity of seenthil chooranam. Result: The study result was concluded that the drug seenthil chooranam has got significant Anthi-histaminic activity. Conclusion: Seenthil chooranam has significant role against the Bronchial asthma.