A Rare Case of Isotopic Phenomenon - Herpes Coster, Lichen Striatus and PMLE

"Wolf's isotopic response" refers to the occurrence of a new dermatosis at the site of previously healed dermatosis. A number of factors including viral, neural, vascular, and immunologic factors have been implicated in the causation of this peculiar response but none has been proven conclusively. The term isotopic response describes the occurrence of a new, unrelated disease that appears at the same location as a previously healed infection.