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Influence of Various Operative Thyroid Techniques on Postoperative Hypoparathyroidism at King Hussein Medical City

Journal: International Journal of Science and Research (IJSR) (Vol.11, No. 7)

Publication Date:

Authors : ; ; ; ; ;

Page : 443-446

Keywords : hypoparathyroidism; operative thyroid technique; thyroid diseases; thyroidectomy;

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Abstract

Background: The main severe risk of thyroid operative techniques is hypoparathyroidism. The frequency percentage of hypoparathyroidism after surgery is 1.6%-50%. In the majority of subjects, this is temporary and only 0.5%-6.6% of subjects might remain with permanent hypoparathyroidism. The operative-induced risk of hypoparathyroidism could be correlated with the size of thyroidectomy influencing hypoparathyroidism after thyroid operative techniques. Aim: To determine the relation between operative thyroid techniques and the risk of postoperative hypoparathyroidism in subjects with thyroid diseases. Methods: Our retrospective investigation included 471 subjects with thyroid surgery for thyroid diseases, of both sexes(women:388 [82.4%], men:83 [17.6%])and aged 35-55yrs.at King Hussein hospital, King Hussein medical city, Amman, JORDAN, during the period 2018-2019. The factors that might affect the risk of hypoparathyroidism such as age and sex were enrolled in the investigation.One-way ANOVA test was used to assess each parameter in groups of operative thyroid techniques. Cox regression was measured to estimate the hazard ratio (HR). Results: Bilateral subtotal (33.3%) was the main frequently used operative technique for thyroid diseases. Nontoxic uni /multinodular goiter is the main frequent disease which needs thyroidectomy (overall = 254/471; 53.9%). 20 subjects (4.2%) with hypoparathyroidism were found. Frequency of hypoparathyroidism was recorded the most in subjects with bilateral total thyroidectomy (4/35; 11.4%) and recorded the least in subjects with unilateral subtotal thyroidectomy (2/82; 2.4%). In subjects with unilateral subtotal, the risk was the most in bilateral total (HR: 10.62), and was the least in bilateral subtotal (HR:1.12). Temporary hypothyroidism was recorded in 15 subjects (75%) and permanent one in 5(25%) subjects. Conclusion: Size of thyroid resection affected the risk of postoperative hypoparathyroidism. Frequency of hypoparathyroidism was recorded the most with bilateral total thyroidectomy and recorded the least with unilateral subtotal thyroidectomy.

Last modified: 2022-09-07 15:19:11