The Study of Hepatoprotective Activity in Alli Chooranam (Nymphea nouchali burm.f)

Background: Alli (Nymphea nouchali burm.f) belongs to family Nymphaeaceae has early history of traditional use, modern research has shown presence of medically active compounds such as tannins, flavonoids, nymphalin etc. Materials andmethods: Ethanolic- water extract of powder of rhizome & flower evaluated for their hepato protective activity on carbon tetrachloride induced hepatotoxicity in rats. Observations: Hepato protective activity results revealed that animals pre - treated with trial drug at both doses 200 mg and 400mg significantly decreased the ALT, AST, ALP, total protein, total cholesterol. Histopathology showed that Alli (Nymphea nouchali burm.f) rhizome & flower extracts induced significant recovery from cellular damage compared to carbon tetrachloride induced group. The most significant activity was observed with Alli (Nymphea nouchali burm.f) rhizome & flower Hydroalcoholic extract at a dose of 400mgkg. The hepatoprotective effect was statistically analyzed by ANNOVA & found to be significant. ( p less than0.05).