Cancer and Complications of Peptic Ulcer in Type 2 Diabetes Mellitus patients at Wasit province, Iraq
Journal: Journal of Medicinal and Chemical Sciences (Vol.6, No. 2)Publication Date: 2023-02-01
Authors : Muna Mohammed Yaseen; Sami Awad Alkubaisy; Walid Theib Mohammad; Abduladheem Turki Jalil; Saja Hussain Dilfy;
Page : 335-345
Keywords : Cancer peptic ulcer; type 2 diabetic; endoscopic test; H.pylori; Bleeding;
Abstract
Diabetes is one of the health challenges for decades, which is concurrent with many pathological disorders. Hence so the aim of the current study aims is to clarify the relationship between type 2 diabetes and peptic ulcers, in addition to knowing its causes and ratio among the population of Wasit city. This study was conducted on 100 patients with type 2 diabetes aged between 20-80 years and 50 non-diabetics with a peptic ulcer as a control group. Medical and laboratory tests to identify diabetes mellitus and peptic ulcers were conducted in at Al-Zahraa General Teaching Hospital. The current study showed that most of the diabetic patients are in the age group from 60 to 80 years, and most of the patients were males (53%). The results of the present research showed that the main leading cause of type 2 diabetes are is a family genetic predisposition to diabetes (44%). Also, exposure of some individuals to a sudden psychological or nervous shock had a role in the occurrence of diabetes by 24%. In our research, 55% of the diabetic patients suffer from peptic ulcers (55/100 persons) and mainly appeared among males (29 males (53%)) compared to females (26 females (47%)). The clinical and laboratory tests showed that Helicobacter pylori (H. pylori) infections were more virulent on in the digestive system of diabetic patients compared to the than non-diabetic patients. The results showed that the occurrence of peptic ulcers in both the stomach and duodenum appeared clearly in diabetic patients, where whereas 42% of diabetic patients had simultaneous ulcers in the stomach and duodenum at the same time. The endoscopic test detected that high-risk hemorrhage Forrest IA, IB, and llA were mainly identified in diabetic patients at a percentage of 18.5%, 15%, and 13%, respectively. Patients with type 2 diabetes have a significant risk for of developing peptic ulcer hemorrhage.
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