Haematological Profile in COVID-19 Infection

In COVID-19 transitory and reversible perturbation of myelopoeisis and granulopoiesis is disordered. Characteristic changes on peripheral blood smear can help in diagnosis, may be in prognosis and treatment protocols. Decrease in lymphocyte count and increase in the neutrophilic lymphocytic ratio (NLR ratio) are the obvious abnormalities detected. Coronovirus mainly affects lungs as most of the ACE-2 receptors are present in lung. Corona has S spikes which helps in attaching it to the ACE -2 Receptor mainly affecting the type II pneumocytes causing capillary leakage and alveolar edema leading to breathing difficulty. COVID-19 is a global pandemic more research is required for prognostication, treatment and diagnostic protocols as disease was an unknown entity before its occurrence