THE USE OF NINTEDANIB IN THE TREATMENT OF POST-COVID-19 FIBROSIS
Journal: International Journal of Advanced Research (Vol.10, No. 09)Publication Date: 2022-09-13
Authors : F. Saroukh H. Mourouth H. Ribahi; G. Eladib;
Page : 64-68
Keywords : SARS-CoV-2 COVID-19 Pulmonary Fibrosis Anti-Fibrosis Nintedanib;
Abstract
Pulmonary fibrosis is becoming a recognized complication of coronavirus disease 2019 (COVID-19). We report 2 cases of 2 patients aged 40 and 61 with pulmonary fibrosis due to COVID-19. The clinical examination showed that the 2 patients were dyspneic with a weak oxygen saturation and that there was bilateral crackles of the two pulmonary fields. High-resolution computed tomography showed bilateral multifocal ground glass opacities, subpleural fibrotic bands (between 25-50% and 75% parenchymal involvement). We prescribed them an anti-fibrosant, nintedanib, and there was a significant clinical and radiological improvement after 15 days of treatment. Nintedanib may have a new therapeutic role in the prevention of fibrosis associated with COVID-19.
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Last modified: 2022-10-04 19:20:44