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Preparation and Characterization and Thermal Study of New Copolymers of Semicarbazide and Fatty Acids Derivatives with Malic Anhydride and Assess their Biological Activity

Journal: Journal of Medicinal and Chemical Sciences (Vol.5, No. 7)

Publication Date:

Authors : ;

Page : 1347-1356

Keywords : Semicarbazide; fatty acids; Malic anhydride copolymers; Thermal study of fatty acid polymer; assential fatty acid semicarbazide;

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Abstract

In this study, new semicarbazide derivatives [E1-E5] were prepared by the reaction of semicarbazide with different fatty acids (olic, linolic, linolinic, recenolic and cinnamic  acid) in DMF, then this compounds will polymerization with malic anhydride in H2O2 as initiator to get [EP1-EP5] .The prepared compounds were characterized by physical properties, UV-Vis, FT-IR, 1H-NMR, 13C-NMR and TGA analysis.TLC checked the purity for these compounds.The antibacterial activity were studied against different kinds  of bacteria, namlyStophylococcuceaures,Stophylococcuce Saprophytic and Protes.

Last modified: 2022-10-09 03:06:05