Metal Complexes of Metronidazole Benzoate with Some Metal Ions: Synthesis and Characterization and Study Apart from Their Biological Applications
Journal: Chemical Methodologies (Vol.7, No. 1)Publication Date: 2023-01-01
Authors : Waleed Alaa Aldeen Saleh; Nada Mutter Abbass;
Page : 81-91
Keywords : Metronidazole benzoate; Metal ions; Antioxidant activity;
Abstract
New metal complexes of metronidazole benzoate were prepared by the reacting of Cd(NO3)2, MnCl2.6H2O and ZrCl4 with ligands in L:M (1:1) mole ratio. All synthesized complexes were analyzed by FT-IR, UV-Vis, TG, DTG, AAS, 1H-NMR, elemental analysis (CHN), melting point determination, magnetic susceptibility determination, and chloride content determination. The proposed shape of all complexes was the octahedral. Some complexes were electrolyte and paramagnetic. All synthesized complexes are activated as antibacterial and antifungal against (Candida, Pseudomonas auroginosa (G-), Escherichia coli (G-), Bacillus (G+), and Staphylococcus aureus (G+)). The antioxidant activity of the ligand was also tested.
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