Blood lipid spectrum and elastic properties of arteries in patients with chronic pancreatitis in combination with arterial hypertension
Journal: Medicni perspektivi (Vol.27, No. 1)Publication Date: 2022-03-30
Authors : Filippova A.Yu. Löhr M. Kryvoshei V.V.;
Page : 42-49
Keywords : blood lipid spectrum; elastic properties of arteries; chronic pancreatitis; arterial hypertension;
Abstract
110 patients aged 45-65 years with chronic pancreatitis were examined. The first group consisted of patients with a combined course of chronic pancreatitis with arterial hypertension; the second group - patients with chronic pancreatitis without concomitant hypertension. All patients were examined for total cholesterol, triglycerides, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and very low-density lipoprotein cholesterol. Arterial stiffness was determined by the pulse wave velocity. It was found that patients of the 1st group had significantly higher levels of triglycerides (37.2%), low-density lipoprotein cholesterol (13%), total cholesterol (25%), atherogenic ratio (19.6%) and significantly lower levels of high-density lipoprotein cholesterol (15.4%). Correlations between age and the level of atherogenic ratio, low-density lipoprotein cholesterol were established – r=0.35; p<0.01; r=0.37; p<0.01, respectively. The duration of chronic pancreatitis positively correlated with the level of triglycerides, low-density lipoprotein cholesterol – r=0.43; p<0.01; r=0.34; p<0.01, respectively. The level of brachial artery augmentation index was significantly lower by 43% in patients with chronic pancreatitis in combination with arterial hypertension, while the aortic augmentation index was significantly higher by 37.6% (p<0.01). It was found that patients of the 1st group had a significantly higher pulse wave velocity in the carotid-femoral segment compared to the 2nd group – by 7.5% (p<0.01). Significant correlations have been established between the brachial artery augmentation index and age, total cholesterol, atherogenic ratio, high and low density lipoprotein cholesterol, triglycerides, cardiovascular risk level by the SCORE scale in patients with a combined course of chronic pancreatitis with arterial hypertension. Conclusions. Patients with the combination of chronic pancreatitis and hypertension had significantly higher levels of triglycerides, low-density lipoprotein cholesterol and total cholesterol. Changes in the elastic properties of arteries in patients with chronic pancreatitis with comorbid hypertension were characterized by an increase in the augmentation index and the pulse wave velocity in the carotid-femoral segment.
Other Latest Articles
- Remodeling of heart in patients with stable ischemic heart disease combined with chronic obstructive pulmonary disease as a basis for development of heart failure
- Community-aquired pneumonia associated with coronavirus disease (COVID-19): determination of pathological process progression predictors by clinical and hemocoagulation parameters
- Analysis of expectations and satisfaction of physicians (provisors)-interns in Ukraine at the stage of primary specialization – internship training
- Analysis of color properties of raster images of histological microspecimens: own research experience
- Research on Algorithm of Mechanical Fault Detection Based on Convolution Neural Network and GMM12
Last modified: 2022-11-02 20:39:29