Synthesis and Characterization of Bis-Flavone Imine Derivatives
Journal: Journal of Medicinal and Chemical Sciences (Vol.6, No. 4)Publication Date: 2023-04-01
Authors : Haider Abbas Alwan; Saadon Abdulla Aowda;
Page : 868-875
Keywords : BIS; flavone imine FT; IR 1H; NMR 13C; NMR Mass spectrum Breast cancer MCF; 7;
Abstract
For different pharmacological activities to treat various diseases, many naturally occurring and synthesized flavonoid derivatives are explored. Certain molecules have drawn the particular interest because of their possible health advantages, such as the antioxidant capabilities of these polyphenolic compounds. By removing free radicals from the environment or chelating metal ions, the functional hydroxyl groups in flavonoids mediate their antioxidant activities. All of the following features are present: antiviral, anti-inflammatory, hepatoprotective, antioxidant, antithrombotic, vasodilating, and anticarcinogenic, along with a high effectiveness and low toxicity. By refluxing one mole of bis-Schiff base chalcone with two moles of DMSO/I2, new bis-flavone imine has been synthesized. Synthesized bis-flavone structures were determined by 1H-NMR, 13C-NMR, and Mass spectrum as well as the anticancer activity (MCF-7) of bis-flavone imine.
Other Latest Articles
- Preparation and Characterization of New Hetrocyclic Azo Thiozal Dye Ligand and Its Use as a Reagent for Determination of Zn+2 Ion in Drug by New Analytical Method
- The Study of BCL11A Gene in Patients with Beta-Thalassemia Major and Intermedia by Random Amplephed Polymorphism DNA in Iraq
- Association of BCL11A Gene Polymorphism in Human Cells of Thalassemia Patient by Evaluation of Amplification Refractory Mutation System (ARMS)
- Synthesis and Characterization of Heterocyclic Compounds-Based Liquid Crystals
- Investigation of Biofilm Formation and Antibiotic Resistant of Bacteria Isolated from Septic Neonates
Last modified: 2022-11-07 06:38:57