WORKING CONDITIONS AND OCCUPATIONAL HEALTH RISK OF WORKERS IN THE ANTICANCER DRUGS PRODUCTION PLANT

Background. Ensuring safe working conditions in the production of medicines is a guarantee of maintaining labor resources and sustainable socio-economic development of the state as a whole. Objective: to study the working conditions and morbidity rates with temporary disability of workers in the shop for the production of anticancer drugs and establish the level of occupational risk to their health. Material and methods. Based on the data of industrial laboratory control of factors of the working environment and the labor process, the results of certification of workplaces, a comprehensive hygienic assessment of working conditions was carried out at 10 main workplaces of the workshop for the production of anticancer drugs in the form of freeze-dried powders and solutions for injections. The source of information for the study of morbidity with temporary disability of workers was the certificates of incapacity for work for a five-year period. The study of morbidity with temporary disability was carried out on two formed groups of workers (the main group - shop workers and the comparison group - employees of management departments). A quantitative assessment of the magnitude of occupational risk was carried out using the results of a study of working conditions, health indicators of employees, data from checking a business entity according to a checklist. Results. The main contribution to the formation of harmful working conditions at a number of workshop workplaces is made by contact with unregulated chemicals, noise, unsatisfactory microclimate parameters in the cold season, and excessive indicators of the severity of the labor process. The level of morbidity with temporary disability of workers in the shop for the production of anticancer drugs was assessed as "medium". The integral indicator among shop workers, taking into account cases and days of temporary disability, did not have statistically significant differences with the average annual indicator in the republic, however, it was higher than in the comparison group (t=2.97, p<0.05). The numerical value of the indicator of the actual level of occupational risk was 1.7. Conclusion. The value of the indicator of the level of occupational risk established in the course of the study indicates the average degree of occupational causation of health disorders among workers in the shop for the production of anticancer drugs in the form of freeze-dried powders and solutions for injections.