A CASE OF NON-MOSAIC ISODICENTRIC Y CHROMOSOME IN A MALE PATIENT WITH ADHD
Journal: International Education and Research Journal (Vol.8, No. 10)Publication Date: 2022-10-15
Authors : Nandita Maini Jindal Mohit Sharma Navjot Kaur Bajwa;
Page : 16-17
Keywords : ADHD; Y chromosome; Isodicentric chromosome; Karyotype;
Abstract
Background: Attention deficit hyperactivity disorder (ADHD) is a childhood neurological disorder more frequently seen in males. The genetics of ADHD is complex and inconclusive. Sex chromosomes are not frequently associated with behavioural disorders. Isodicentric Y chromosome though a relatively common anomaly is mostly mosaic and reported frequently in infertile males. Case Description: A 16-year-old male with ADHD had presented to our hospital with complaints of having difficulty in coping up with academics at school. The patient showed a karyotype of non-mosaic 46,X,idic(Y)(q12). Conclusion: This is a rare case of non-mosaic isodicentric Y chromosome seen in a phenotypically normal male patient with ADHD.
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