PATTERNS OF ADJUVANT TREATMENT FOR ENDOMETRIAL CANCER : THE EXPERIENCE OF A SINGLE INSTITUTION IN MOROCCO

Endometrial cancer is the fourth most common malignant tumor in women in developed countries, and in Morocco it represents the third most common gynecological cancer. It primarily affects postmenopausal women. Our study is a retrospective descriptive study conducted from 01/01/2014 to 01/01/2018 at the radiation therapy department of the National Institute of Oncology in Rabat. Data were collected from medical records and included epidemiological, clinical, therapeutic and prognostic aspects of this cancer. The median age at diagnosis was 61 years. The median delay to consultation was 6 months. The histological diagnosis was made by endometrial biopsy in 52.3% of cases. Pathological examination revealed endometrioid adenocarcinoma in 91% of cases. 32 patients received adjuvant treatment consisting of external radiotherapy at a dose of 46 Gy in 23 fractions, followed by vaginal brachytherapy (37%), of which 6 of these patients also received sequential chemotherapy (7.1%). 21 patients were treated with brachytherapy alone (25%), 11 patients with external radiotherapy alone (13%), and 21 patients with concurrent radiochemotherapy (25%). The treatment interval between diagnosis and surgery was 42 days. In our series, the overall 5-year survival rate was 93.6% for all stages combined.