Synthesis, Spectral, Cancer Inhibitory Activity and Antimicrobial Studies of Cobalt(II) and Nickel(II) Metal Complexes Containing Azo Derived from 2-Amino Benzimidazole
Journal: Journal of Medicinal and Chemical Sciences (Vol.6, No. 8)Publication Date: 2023-08-01
Authors : Neda Hasan; Muhammed Abdel Hasan Shallal; Hayfaa A. Mubarak; Mustafa M.Karhib; Ahmed S Naje;
Page : 1885-1896
Keywords : Synthesis Imidazolylazo dye Spectrum studies Breast cancer (MCF; 7);
Abstract
The production of the tridentate Azo ligand 2-[2/-(benzimidazolyl)azo]-4-bromo-6-chloro phenol (BIABrClP) complexes using Co(III) and Ni(II) is discussed in this article. Spectral methods including 1H-NMR, UV-Vis, FT-IR, magnetic moment measurements, molar conductance, and elemental analysis were used to thoroughly explore the coordination mode of azo ligand containing NNO donor atoms with metal ions. The octahedral geometry for the synthesized Ni(II) and Co(III) complexes was suggested from the analytical and spectral studies. According to in vitro assays for antibacterial activity, the majority of produced compounds exhibit good action against a variety of microorganisms, including Candida albicans, Staphylococcus aureus, and Escherichia coli.
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Last modified: 2023-04-06 17:43:01