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Ammonium Chloride Catalyzed Green Synthesis, Characterization of Substituted 1-H-Indazole Derivatives

Journal: Journal of Applied Organometallic Chemistry (Vol.2, No. 1)

Publication Date:

Authors : ; ; ; ;

Page : 7-14

Keywords : 1-H-indazole EtOH; Hydrazine hydrate; NH4Cl; Grinding;

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Abstract

We have demonstrated novel and eco-friendly acceptable green methods for the synthesis of numerous 1-H-indazole by grinding protocol using NH4Cl  milder acids in an EtOH solvent.  The substituted 1-H-indazole synthesized from the grinding of ortho-hydroxybenzaldehyde with hydrazine hydrate in an Ethanol solvent and NH4Cl  milder acids.  The methods give good yield within less time. The protocol is practically green, milder, higher yield, with short reaction times.

Last modified: 2023-04-18 09:05:27