ROLE OF ANTIBIOTIC IMPREGNATED CEMENT COATED INTRAMEDULLARY NAILING IN ORTHOPAEDICS
Journal: International Journal of Advanced Research (Vol.11, No. 03)Publication Date: 2023-03-16
Authors : Pradeep Choudhari Charchit Baurasi Deepesh Mehta; Manish Patidar;
Page : 1421-1428
Keywords : Antibiotic Cement Nailing Infection Non-Union;
Abstract
Introduction:Traditionally,thetreatmentstrategyofinfectednon-unionconsistedofsurgicaldebridementandthenasecondprocedureforstability.Theuseofanantibioticcementednailingforinfectednon-unionoftibiaandfemurfracturesavoidstheneedofmorethan1procedureasthenailprovidesstabilityandallowshigherconcentrationofantibioticatthelocalsitethanisachievablewithsystemicantibioticsandisassociatedwithfewersideeffect. MaterialandMethods:Thisisaprospectivestudyof12patientswithdiaphysealfractureoftibiaorfemurwithsignsofinfectionwhoweretreatedusingantibioticcementednailing.Patientswerefollowedupmonthlyfor3months.Infectioncontrolwasevaluatedintermsofclinical,haematologicalandmicrobiologicalparameters. Results:Atthetimeofpresentation11outof12patientshadpusdischarge,whilelocalriseoftemperaturewasthereinallpatients.MostcommonorganismthatwasisolatedincultureswasStaphylococcusaureus.ESRandCRPwaselevatedin9patients.At3monthsfollowupvisit,9outof12patientsresolvedallsignsofinfectionwhile1hadpersistentpositiveculturereports.ESRandCRPwasraisedin3and2patientsrespectively. Conclusion:Antibioticcementednailingdeliversahighconcentrationofantibioticsatthelocalsitewithoutcausinganysystemictoxicityalongwithprovidingstabilityatthefracturesite,therebyconvertingatwo-stageprocedureintoasinglestageprocedurewhichalsoavoidscomplicationsofexternalfixatorhavingbetterpatientcompliance.
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