HAIR GROWTH PROMOTING ACTIVITY OF HELIANTHUS ANNUUS IN TESTOSTERONE INDUCED ALOPECIA IN MICE MODEL

To study the hair promoting activity of Helianthus annuus in testosterone induced alopecia in mice model. Objective: The objective of this research include to find an alternative for present allopathic medication to minimize side effects and adverse drug reactions, there is no study has been carried out on Helianthus annuus so far Therefore, the present study used to evaluate hair growth promoting activity using testosterone induced alopecia. Material and Method: Swiss albino mice of either sex weighing 25-30 gm were used. Minoxidil (2%) solution purchased from market. This is the standard drug used for Alopecia. Testosterone (1ml ampoule) were purchased from Matoshri medical, Walgaon. It is used to induced alopecia in mice. Result: The histological study showed that hair density was maximum i.e. 2.833 ± 0.1667 in case of standard, 2.167 ± 0.1667 in case of Helianthus annuus oil 100ml/kg, 2.667 ± 0.2108 in case of Helianthus annuus oil 200 ml/kg, 2.167 ± 0.1667 in case of Negative control group while it was minimum i.e. 1.167 ± 0.3073 in testosterone treated animals.