SARS-CoV-2-Infection in Children and Newborn: Less Severe Than in Adults? |Biomedgrid
Journal: American Journal of Biomedical Science & Research (Vol.8, No. 3)Publication Date: 2020-03-19
Authors : Stefan Bittmann; Elisabeth Luchter; Anne Weissenstein; Gloria Villalon;
Page : 194-194
Keywords : Corona; virus; Infection; Pandemic; Pneumonia signs;
Abstract
First reports shed light on cases in newborn and children, mostly published by chinese medical doctors and researchers. Few reports described first small series of SARS-CoV-2 infections in pregnant women, who delivered SARS-CoV-2 negative babies [5,6]. A number of 190.000 new cases of CoV-2-pneumonia have been reported in adults, including 7807 deaths (date 19/03/2020). In children and neonates, no death was described so far. A possible explanation for this entity could be immature angiotensin II receptors, the primary docking site of spike protein of SARSCoV- 19 virus. SARS-Cov-2 infections results in a loss of human life and economy [1,4]. Till the beginning of march 2020, 285 children with SARS-COV-2 pneumonia and 10 newborns were reported to have been diagnosed in China [5,6]. Epidemiological investigations suggest that people are generally susceptible to SARS-COV-2, and some children have a clear family gathering history [2,3]. The national health commission presented in the “corona virus infection pneumonia treatment plan“, that children and infants also have the disease (March 2020). The symptoms of some children and neonates are variable, presenting as vomiting and diarrhea and other gastrointestinal symptoms or only showing as weak spirit and shortness of breath. Children with mild symptoms only showed low fever, mild fatigue, and often no pneumonia signs.
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