Bionic Eye from the Point of View of Functional Magnetic Resonance and Electrophysiological Examination – Review |Biomedgrid

The aim of the study was to show not only a possible visual replacement in patients with loss of sight, but also to discuss its efficiency. The study is focused on the issue of transmission of electrical voltage changes in the visual pathway under physiological and pathological conditions. In particular, it points to the feedback autoregulatory damage, not only of the primarily altered cellular structures, but also of all other structures localised both horizontally and vertically. Based on the results of the functional magnetic resonance imaging and electrophysiological methods, it demonstrates the pathology of the entire visual pathway in three important eye diseases: pigmentary retinal dystrophy, age-related macular degeneration, and glaucoma. The study also provides an overview of possible systems used to replace loss of vision, ranging from epiretinal, subretinal, suprachoroidal implants to stimulation of the optic nerve, lateral geniculate nucleus and visual cortex. Regarding the pathophysiology of neurotransmission, it is assumed that recovery of sight using these systems is not possible.