Estimation of the Cartilage Volume Loss Due to Knee Osteoarthritis - Case Study

Osteoarthritis (OA) is a degenerative disease of the knee joint caused by the formation of cracks within the collagen fibers of the articular cartilage. Current research is directed towards less invasive procedures for treating this degenerative disease using tissue engineering and 3D bioprinting. Therefore, it is crucial to obtain the exact shape of the damaged tissue, reconstruct the original shape of the tissue, and estimate the volume and area resulting from the wear of the contact surfaces. The study used the tibial plateau of a patient with OA that was removed during total knee arthroplasty, and the data was collected using a 3D scanner. After the reconstruction of the tibial plateau, an assessment of the area and volume of wear on the medial condyle of the tibia was performed, along with a FEM analysis of the real and approximate shape of the cartilage tissue. In this way, it is possible to simulate and create a patient-specific 3D model with a reconstructed wear volume, which can be highly attractive for future treatment strategies for cartilage damage or early stages of OA.