Molecular Chirality as an Integral Biomarker of Lactation, Nutrition and Cognitive Development Express-Review |Biomedgrid
Journal: American Journal of Biomedical Science & Research (Vol.8, No. 6)Publication Date: 2020-05-05
Authors : Victor V Dyakin; Eva V Posner;
Page : 545-549
Keywords : Lactation; Enzyme; Serine Racemase; Racemization; Post-Translational Modification;
Abstract
It becomes an axiom that all living organisms are composed predominantly of L-amino acids (L-AAs) and D-sugars. However, in many biomedical studies, there is a significant discrepancy between the amount of available information regarding D-AAs biology and a degree of pragmatic implementation. It is applying to the fields of nutrition and lactation. The mutual interaction of internal and environmental sources of D-AAs in an organism, including the food, microorganisms, is influenced by the spontaneous and enzymatic racemization. The interacting sources of D-AAs are recognized as an essential determinant in the embryonic/infant development, the lifestyle of an adult an organism, and aging. Progress in the analytical methods of chiral discrimination is promising to revolutionize the field of neuroscience, neurodegeneration, psychology, drug production, and the food industry, which should be reflected in the field of lactation. However, the attention to the D/L AAs balance in the area of breastfeeding is overlooked until the present. In short, our aim is predicting the importance of the serine racemase (SerRs) enzymes in human breast milk production and digestion.
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