Effect of Androgen Use among Children with Micropenis in Erbil City

Background and objective: Micropenis is a condition where the penis is smaller than average, causing psychological distress and affecting sexual function. The aim of this study was to determine the effect of androgen therapy on gonadal response and penis growth in children with micropenis. Method: This was a retrospective and prospective study including a sample of 30 children in the age range of 9-13 years old with micropenis from March 2019 to December 2022 in Erbil, Iraq. Informed consent was obtained from the legal guardian of the children. Demographic information, drug dosage, testosterone level, and penis length were collected and recorded before and after the therapeutic intervention. All participants received a therapeutic regimen involving Sustanon 250 mg/1ml injections. Result: In this study, the age of the patients participating in the study was between 9 and13 with an average (standard deviation) of 11.176 ± 0.567 years old. The number of treatment doses varied, with 16.7% receiving one dose, 33.3% receiving two doses, and 50% receiving three doses. Testosterone levels significantly increased from a mean of 0.024 ± 0.007 ng/dl before the intervention to 0.883 ± 0.318 ng/dl after (p ≤ 0.001). In addition, penile length significantly increased from a mean of 16.983 ± 1.923 mm before the intervention to 36.7 ± 3.485 mm after (p ≤ 0.001). Conclusion; Androgen can be useful in the treatment of micropenis because the results showed that it increased both the testosterone level and the penis length.