Ameliorative Effects of Dried and Germinated Fenugreek Seeds on Kidney Failure Induced by Gentamicin in Male Mice |Biomedgrid

Gentamicin is an aminoglycoside antibiotic widely used against Gram-negative microorganisms. Nephrotoxicity is the main limitation to its therapeutic efficacy. The aim of work was to investigate the role of dried and germinated fenugreek seeds as a potent antioxidant against the nephrotoxicity and oxidative stress in the kidney. Male Swiss albino mice were divided into The animals were injected intraperitoneally with distilled water. The animals were intraperitoneally injected with gentamicin. The animals were orally received fenugreek (Trigonella foenum -graecum) The animals were orally received germinated fenugreek. The animals were intraperitoneally injected with gentamicin simultaneously with fenugreek (Trigonella foenum -graecum). The animals were intraperitoneally injected with gentamicin simultaneously with germinated fenugreek.