“Identification of SARS-CoV-2 in Human Genome based on Protein Dynamics Conversion and Target Genes Marking via Bioinformatics Approaches”
Journal: Bioinformatics & Proteomics Open Access Journal (BPOJ) (Vol.5, No. 1)Publication Date: 2021-06-30
Authors : Vinita Srivastava Shashi Prabha Agrawal Nandita Trivedi Alka Dubey Sunil Kumar Mishra Kanchan Chaurasia; Swinderjeet Singh Kalra;
Page : 1-13
Keywords : Coronavirus; miRNAs; SARS-CoV-2; Precursors; Transmission;
Abstract
In this project our team worked on identification of target genes in human from Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and Human-to-human transmission of SARS-CoV-2 was confirmed on 20 January 2020 during the COVID-19 pandemic Transmission was initially assumed to occur primarily via respiratory droplets from coughs and sneezes within a range of about 1.8 meters (6ft). Laser light scattering experiments suggest that speaking is an additional mode of transmission and a far- reaching and under-researched one, indoors, with little air flow. Other studies have suggested that the virus may be airborne as well, with aerosols potentially being able to transmit the virus the first known infections from SARS-CoV-2 were discovered in Wuhan, China. The original source of viral transmission to humans remains unclear, as does whether the virus became pathogenic before or after the spillover event and we also found numbers of genes specific targets in human via bioinformatics approaches based on symptoms and its analysis. Identification of genes based on miRNA analysis of corona virus sequences. First we prepared some precursors sequences including analysis of genomics values after based on alignment similarly of short lengths nucleotide sequences in a form of miRNAs via bioinformatics approaches then we predicted targeted genes in a whole human genomes from the miRNA of corona virus and we identified some potential genes based on symptoms of corona virus infected peoples.
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