The Role of Detection of the Association of FGB Gene (Rs1695) Iie 105 Val Polymorphism Genotypes in Pregnant Women with Fetal Loss Syndrome in Uzbekistan |Biomedgrid

With the development of a genetic approach to the study of the etiology and pathogenesis of many diseases, including FPI, great importance has been attached to congenital or hereditary disorders in the processes of storage, transmission, and realization of genetic information. In a view of the priority of endothelial dysfunction in the FPI genesis , the importance of the vascular system, as the main diagnostic feature of the disease, and findings of previous studies on the genetics of this pathology, namely the existence of polymorphism of the “vascular system” and “endothelial dysfunction” genes in many ways can explain the obvious individual differences in origin and course of the disease. The aim oof our research was to determine the frequency of polymorphisms of hemostasis and fibrinolysis genes: FGB in pregnant women in Uzbekistan.