BCG Vaccine in Relation To COVID-19 Morbidity and Mortality |Biomedgrid

The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS CoV-2) significantly interrupts daily life activities leading to global social and economic disruption. The infected cases and deaths due to COVID-19 are continuously rising. The lower incidence of COVID-19-cases among countries with Bacillus-Calmette-Guérin (BCG) vaccination background raises the possibility that BCG vaccine could be a protective against COVID-19. Here, we studied the prevalence of COVID-19-cases in relation to population received BCG vaccination. The collected data were compared at two different time points for proper validation and execution of appropriate association. Our investigations showed a correlative association between BCG vaccination and the number of COVID-19-cases. The association obtained can be supported by the fact that BCG vaccination is associated with an increase in trained immunity.