Occurrence of Microbial Resistence in Blood Cultures in a Teaching Hospital before and after the Restrictive Measure for the Commercialization of Antimicrobials in Brazil

Bacterial resistance to antimicrobial drugs (ATM) has become a global public health problem. The collegiate board of the National Health Surveillance Agency (ANVISA) through RDC 44, published on October 26, 2010, determined that prescribed antibiotics can only be dispensed with special control prescription, aiming to restrict the free access to these drugs and minimize the microbial resistance. The present study aims to identify microbial resistance in blood culture in hospitalized patients before and after the implementation of restrictive measurement. We observed decrease in the occurrence of blood culture microbial resistance in Phase II (0,62 for 100 people day) compared with Phase I (0,75 for 100 people day).