A Review Article on Oral Mucosal Drug Delivery System
Journal: International Research Journal of Pharmacy and Medical Sciences (IRJPMS) (Vol.6, No. 4)Publication Date: 2023-07-15
Authors : Sudhir Priyadarshi; Shaffi Khurana Tangri;
Page : 25-29
Keywords : ;
Abstract
A New Drug Delivery, such as a Mucoadhesive System, can enhance the effectiveness of drugs, by eliminating Enzymatic degradation and first-pass metabolism caused by Gastro intestinal region, oral mucosal drug delivery system are frequently used as a Novel site for administration of drugs for Immediate and Controlled release. A sophisticated method called mucoadhesion that uses a polymer drug delivery system involves polymer chain interaction through Wetting, Adsorption and Other Mechanisms. Many polymer based characteristics including the level of Cross-Linking, Chain Length, and existence of different Functional Groups, have an Impact on the Effectiveness and Degree of Mucoadhesive Binding. By maintaining Intimate Interaction with the tissue that absorbs, the mucosal surface release the medicine at the site of action, improving both Local and Systemic Effects. The mucosa contains number of blood stream and is Comparatively permeable. The mucosa of the buccal cavity is ideal due to its Accessibility, Smoothness, Immobile Surface, and Bioadhesion System Suitability. Moreover, It is conceivable to provide medication to individuals who are unconscious and uncooperative. It covers a variety of dosage forms with different combination of polymers and Absorption Enhancers, such as adhesive Patches, adhesive Gels, adhesive Tablets and many more
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Last modified: 2023-07-12 19:59:49