Aegle Marmelos (L.) Correa, A Potential Source for the Treatment of Diabetes Associated Alzheimer’s Disease: A Review

Alzheimer's disease is a chronic neurodegenerative disorder leading to memory loss, which is caused by progressive wasting away of brain cells. Memory loss leads to changes in a person's behavior, thinking and social skills leading in turn to profound alterations in a person's social and family life. The disease can occur by itself with age; however, onset of diabetes can precipitate the onset of the disease or augment the disease process and symptoms. Current allopathic medications can only improve the symptoms of Alzheimer's disease, albeit temporarily and cannot cure the disease. According to the World Health Organization, about 44 million people were suffering from the disease in 2015, a number likely to go up to 114 million by 2050 causing severe strains in family relationships and finances. Plants are a potential source of stopping the development of Alzheimer's or even curing the disease. The present review examines the potential of a plant Aegle marmelos or Bengal quince in the treatment of Alzheimer's disease.