Novel Vesicular Drug Delivery Systems Proniosomes

These proniosomes, which are dry surfactant-coated particles that form niosomal dispersion in hot aqueous fluids immediately on stirring, are the subject of this review paper. It is easier to transport, distribute, store, and administer dosage forms such as proniosomes thanks to their provesicular structure, which reduces the issues of vesicular system physical stability such as aggregation, fusion, and leakage. Lipophilic or amphipilic medications can be delivered effectively by oral route using proniosome powders, which are suitable dosage forms. Proniosome preparation, characterisation, release profile, applications, advantages, and downsides are all discussed in this review in great detail.