Acral Peeling Skin Disease: About 2 Cases

Acral peeling skin syndrome is a rare, autosomal, recessive genodermatosis characterized by painless spontaneous exfoliation of the skin of the hands and feet at a subcorneal or intracorneal level. We are reporting 2 cases of spontaneous asymptomatic peeling skin limited to the acral surfaces especially the soles of the feet. Skin biopsy showed slight separation between the granular and corneal layers, with no inflammation. Both of them were treated with emollient and a slight improvement has been noticed.