Broad Spectrum Antiviral Therapy can Supersede Vaccination Strategy for Combating COVID-19 Pandemic

As of today seven coronaviruses were identified to infect humans, out of which only 4 of them belongs to beta family of coronavirus, like HCoV-HKU1, SARS-CoV-2, MERS-CoV and SARS-CoV. SARS family viruses were known to cause severe respiratory disease in humans. SARS-CoV-2 has recently considered as a pandemic with over 100 M confirmed cases and over 1.5 M death worldwide. Vaccines and antibodies appeared as record pace. However, generation of variants has already been demonstrated as an escape of virus from a particular vaccine therapy. Therefore, a broad-spectrum anti-CoV therapies should be emphasized.