JUVENILE LYMPHOSARCOMA IN CALF: A CYTOHISTOLOGICALANALYSIS

Bovine lymphosarcoma is one of the most prevalent neoplastic diseases in cattle, which affects both dairy and beef animals. Serological evidence and molecular characterization of Enzootic bovine leukemia are reported from India, but reporting of juvenile lymphosarcoma in the calf is scarce. A four-month-old female HF Cross calf with depression, progressive weight loss, weakness, and enlarged peripheral lymph nodes were brought for treatment to the Veterinary Clinical Complex (VCC), SKUASTJ, Jammu, R.S. Pura, India. Peripheral blood showed leukocytosis, lymphocytosis, and normocytic, normochromic anemia. Blood smear and cytopathological examinations revealed the presence of atypically large lymphocytes with obvious clear cytoplasmic vacuoles and cleaved, reniform, amoeboid nuclei with unclear nucleoli. Histopathological examination of the affected lymph nodes showed the presence of a tumor that was characterized by proliferating round, distinct pleomorphic cells having minimal cytoplasm, prominent nuclei, and oval and round basophilic shapes. On the basis of cytological and histo-pathological basis, the present case was described as sporadic juvenile lymphosarcoma.