Full Blood Count Estimation Using Abbott Cell-Dyn Ruby 5-Parts in Comparison with Boule Medonic M-Series 3-Parts Differential Haematology Analyser |Biomedgrid

Full Blood Count (FBC) is a significant laboratory investigation often requested in clinical care and trials; laboratories should have comparable alternative methods for this test to ensure uninterrupted services. This study evaluated to what extent the Abbott CELL-DYN Ruby and Boule Medonic M-series haematology analysers can be used interchangeably. Using 110 leftover EDTA blood samples to test twelve haematological parameters, correlations and bias between the two analysers for each blood parameter were determined by plotting Passing & Bablok and Bland-Altman's plots respectively. The two analysers were assessed comparable for a test when the bias with the 95% CI falls within the clinically acceptable limits which had been defined a priori. All the twelve FBC parameters showed strong positive correlations between the measurements from the two analysers. The measurements on both analysers however showed some bias for all the parameters evaluated except Red Blood Cells (RBC), whose bias was 0.00 x 10-12/L (-0.01, 0.02).