Lung Inflammatory Myofibroblastic Tumor Carrying TGF -ROS1 Fusion: About a Case |Biomedgrid

This is a 48-year-old patient hospitalized for management of an intracranial hypertension syndrome whose radiological assessment was in favor of metastatic brain lesion with primary pulmonary origin, the biopsy with anatomopathological study posed the diagnosis of ‘' an inflammatory myelofibroblastic tumor associated with a TGF-ROS 1 fusion ALK-negative, the patient benefited from treatment with a targeted therapy based on crizotinib with good clinical response, in particular the regression of symptoms and radiological response, patient currently still under treatment.