Novel Approaches to Clinical Trial Design and Implementation

Companies are working hard to adopt and execute efficient and innovative approaches to accelerate drug releases, giving the clinical research sector a big makeover. The difficulty of powering and recruiting participants into a study in a small and frequently heterogeneous population, the dearth of natural history data informing crucial design elements, and the ethical and recruitment difficulties associated with assigning patients to a placebo arm are all obstacles to the clinical development of new therapies. The goal of this article is to present innovative clinical trial design methods, including adaptive designs, Bayesian techniques, and master protocol designs basket and umbrella designs . It is intended that this review will increase knowledge of these methods and promote their application in research. R. Saraswathi | Rabin Kumar Parida "Novel Approaches to Clinical Trial Design and Implementation" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-7 | Issue-2 , April 2023, URL: https://www.ijtsrd.com.com/papers/ijtsrd56252.pdf Paper URL: https://www.ijtsrd.com.com/other-scientific-research-area/other/56252/novel-approaches-to-clinical-trial-design-and-implementation/r-saraswathi