Insulin Receptor-Associated Roles of Serotonin Transporter |Biomedgrid
Journal: American Journal of Biomedical Science & Research (Vol.12, No. 1)Publication Date: 2021-02-16
Authors : Fusun Kilic;
Page : 70-72
Keywords : Serotonin transporter; Mechanism; Apoptosis; Glycosylation; Maturation;
Abstract
Insulin signalling plays a major role in maturation and the translocation of serotonin transporter protein (SERT) to the plasma membrane through acting on endoplasmic reticulum (ER) proteins, specifically ERp44. In supporting these reports, SERT was found as arrested at intracellular compartments in diabetes associated placental cells.
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