The Ratio of Dialysate NGAL to Plasm NGAL (NGAL D/P) Can Reflect Peritoneal Transport in CAPD Patients |Biomedgrid

Objectives: To probe the role of peritoneal NGAL in reflecting peritoneum function. Methods: 20 CAPD anuria patients without peritonitis in our peritoneal dialysis center were recruited from July 2016 to July 2018. These patients were divided into high-transport peritoneum group and non-high transport peritoneum group according to peritoneal transport type. Patients from both groups received the same dialysis solutions and dialysis modality. Peritoneal transport type, serum C-reactive protein, peritoneal equilibrium test results, dialysate NGAL, plasm NGAL, the ratio of dialysate NGAL to plasm NGAL (D/P NGAL) from both groups were recorded. Spearman's correlation coefficient was employed to examine the relations between variables. Receiver operating characteristic (ROC) curve analysis was used to calculate the area under the curve (AUC) for ratio of dialysate NGAL to plasm NGAL (D/P NGAL) and peritoneal creatinine to serum creatinine (D/P creatinine).