Rhabdoid Signet- Ring Mixed Cell Subtype Gastrointestinal Stromal Tumor from the Stomach - Pathohistological and Immunohistochemical Analysis, Differential Diagnosis, Prognosis and Complex Treatment |Biomedgrid

We present rarely diagnosed extremely malignant rhabdoid signet- ring mixed cell subtype gastrointestinal stromal tumor (GIST) from the stomach in a man of 67 years. This is a third rhabdoid histological phenotype GIST posted in the English medical literature. The diagnosis is placed after a pathochistological and immunohistochemical analysis of the lung biopsy material. The purpose of this presentation is to discuss the difficulty early diagnostics, the prognosis of this extremely malignant GIST, the differential pathohistological and immunohistochemical diagnosis with other benign and malignant tumors. The diagnosis of a GISTs is directly related to treatment with a tyrosine kinase inhibitor (Imatinib), which is indicated for inoperable and metastatic GIST.