Methanol Leaf Extract of Desmodium Velutinum (Wild.) D.C. and Acarbose Exhibit Additive Pharmacological Effects in Diabetic Wistar Rats |Biomedgrid

This study investigated the pharmacological effects of methanol extract of Desmodium velutinum leaves (DVE) administered alone and when co-administered with Acarbose (ACA) in diabetic Wistar rats. Preliminary phytochemical analysis and acute toxicity study were carried out on DVE using standard methods. In the pharmacological study, diabetes was induced in rats by intraperitoneal administration of 150 mg alloxan/kg b.w. Seven groups (6 groups of diabetic rats and 1 group of normoglycemic rats) of four rats each were used for the study.