The Relationship Between Toxoplasmosis and Breast Cancer |Biomedgrid

Toxoplasma gondii is upiquitous, obligatory, intracellular parasite causing a serious and common disease known as toxoplasmosis. It is one of the common zoonotic parasites between humans and animals and causes serious problems for humans, especially immunosuppressed people [1]. T. gondii is still a risk on animals and human health in the world due to it is uncontrolled until now because to it′s a complexity of its lifecycle which include a sexual cycle in epithelial cells of cat's intestine and asexual cycle in birds & Mammals involving human [2]. This parasite is still a real danger to human and animal health due to the complexity of its life cycle, which includes a sexual cycle in epithelial cells of the cat's intestine, which produces sporozoites, and an asexual cycle in birds and mammals (humans), which produces bradyzoites & tachyzoites [3]. All phases contain a unique virulence component that allows it to influence the immune system and form a persistent infection. Furthermore, until today, there has been no widely acknowledged human vaccination against toxoplasmosis [4]. Breast cancer is the most frequent disease in women worldwide, accounting for 23% of the 1.1 million new women cancer diagnoses each year. It is additionally the biggest causing of cancer-related fatalities worldwide, with low-resource countries having the greatest case fatality rates. Breast cancer has claimed the lives of over 4.4 million women in the last five years, making it the most common cancer in women, making breast cancer in women the most prevalent cancer globally.