EXPLORING THE DEVELOPMENT OF DENDRITIC CELL-BASED CANCER VACCINES WITH A FOCUS ON CANCER RESEARCH
Journal: International Journal of Advanced Research (Vol.11, No. 09)Publication Date: 2023-09-19
Authors : Sudeepthi Rongali Sravani Ponnam Mahiswar Reddy Desireddy Geeth Chand Sai Yanamadala Anupama Cherukuri Sadashiva Sreehitha Ediga; Praveen Kumar Vemuri;
Page : 1248-1256
Keywords : Cancer Vaccine Dendritic Cell APC Tumour Immunity;
Abstract
The fundamental premise behind clinical approaches for dendritic cell mediated immunization in cancer is that the limiting defect in natural antitumor immunity is at the level of antigen presentation. In contrast to vaccines for the prevention of infections, cancer vaccines are administered in a therapeutic mode, to eradicate antigen-bearing tumor cells already present in the host. Over decades, the identification of antigens that can serve as targets for immune effectors have resulted in a profusion of strategies for activating tumor antigen-specific immune responses. Therapeutic vaccines, unlike prophylactic vaccines for the prevention of infections, all share some basic attributes, the presence of target antigens, and a method for delivering the antigen into the antigen-presentation machinery in conjunction with other molecules required to provide T- and/or B-cell activation.
Other Latest Articles
- LIFESTYLE IN SPACE HABITAT
- RESPONSES OF RMG PRODUCERS IN BANGLADESH TO MULTINATIONAL BUYERS DEMAND DURING COVID-19 PANDEMIC
- HUMAN ONTOLOGY FROM THE VIEWPOINT OF ORTHODOX CHRISTIAN ANTHROPOLOGY AND THE PSYCHOANALYTIC APPROACH
- CYTOTOXIC AND GENOTOXIC EFFECTS OF UV IRRADIATION ON ROOT MERISTEM CELLS OF ALLIUM CEPA L
- NON CASEATING NON GRANULOMATOUS TUBERCULOUS LYMPHADENITIS : A CASE REPORT
Last modified: 2023-11-04 20:00:16