Use of Hyaluronic Acid for Rotator Cuff Tendinopathy |Biomedgrid

The tendon healing process is slow and structured in multiple phases, from inflammatory cytokine recruitment to growth factors and reparative cell involvement. As a result of the healing process, it is widely known that there is the frequent formation of inferior quality fibrotic scar tissue or fibrous adhesions, which modify the structure and function of the tendon. Beyond preventive measures, therapeutic strategies in the case of persistent lesions include biomechanical corrections, anti-inflammatory drugs, instrumental therapies such as shock wave or electromagnetic field stimulation, and recent regenerative stimulation therapies. These regenerative therapies such as hyaluronic acid (HA), platelet-rich plasma (PRP), or growth factors (GFs) aim to stimulate an anabolic environment. It is important to recall that some tendon lesions are require surgical treatment according to the tear type, and in this setting, the role of regenerative therapies would be to enhance the operative results.