Hepatic GIST Tumor with Cystic Morphology: A Case Report and Literature Review |Biomedgrid
Journal: American Journal of Biomedical Science & Research (Vol.14, No. 4)Publication Date: 2021-10-14
Authors : Blaire A Anderson BS; Anna S Bouck BA; Bing Ren MD PhD;
Page : 390-394
Keywords : Gastrointestinal stromal tumor; Extraintestinal gastrointestinal; Stromal tumor; Cystic morphology; Treatment;
Abstract
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal-origin tumors of the gastrointestinal tract. They arise in the interstitial cells of Cajal, the cells that generate peristaltic motions. GISTs can demonstrate a variety of genetic mutations including KIT and PDGFRα mutations. They are most frequently located in the stomach (60-70%), small intestine (20-25%), colon and rectum (5%), and esophagus (<5%). Nearly half of all patients diagnosed with GIST will experience recurrence or metastasis-most commonly to the liver or peritoneum. Primary and metastatic GISTs typically present as solid masses. Cases of metastatic and primary liver GIST with cystic morphology are exceedingly rare. Here we present a case of presumed metastatic liver GIST in a patient with a large, symptomatic, cystic liver mass and review other published cases of hepatic GIST with cystic morphology.
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