Mortality and Prevalence of COVID-19 in Variable Cancer Subtypes with Radiological Correlation at the King Hussein Cancer Center
Journal: Journal of Medicinal and Chemical Sciences (Vol.7, No. 2)Publication Date: 2024-02-01
Authors : Mousa El Khaldi; Mira Al Jabi; Dana Alkhulaifat; Mais Zmaily; Maysa Al-Hussaini; Mariam Kharroubi; Tala Ghatasheh; Samar Taqatqeh; Abdallah Nofal;
Page : 352-362
Keywords : COVID; 19 Cancer Mortality rate Radiological findings;
Abstract
Purpose: Radiographic abnormalities on first CT scans may correspond with increased risk of severe COVID-19 infections in cancer patients. Therefore, the purpose of this study is to use CT scans to identify the radiological characteristics of COVID-19 in deceased cancer patients from Jordan's King Hussein Cancer Centre (KHCC), and to quantify the mortality rate in a subgroup analysis of individual cancers, all while comparing our findings to the existing literature.
Methods: The inpatient and outpatient records of 785 patients diagnosed with cancer who tested positive for COVID-19 by RT-PCR between September 2020 and December 2020 were reviewed, along with the chest CT scans of 24 patients who died of the disease. Microsoft Excel 2013 was used for all data analysis. We just make use of descriptive statistics.
Results: In total, 82 (10.5%) of COVID-19-positive cancer patients passed away. Patients' median ages at death were 58.8 15.5. There were 38 male deaths (47.3%) and 44 female deaths (53.7%). In our research, COVID-19 was most frequently associated with diagnoses of breast cancer. Patients with gastrointestinal (GI) cancer and hematological cancer had the highest rates of death due to COVID-19. Multiple myeloma patients had the greatest mortality rate compared to the total number of cases. Ground glass opacities with or without consolidations were the most often observed CT finding in the deceased. CT scans showing pleural effusion were more common in patients with severe COVID-19 infection.
Conclusion: COVID-19 clinical features of KHCC cancer patients are assessed in this study. Patients with COVID-19-related malignancy had a low overall death rate, and the radiological findings of COVID-19 in the deceased were determined to be typical for the population as a whole.
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