EXPERIMENTAL STUDY OF ATIBALA (ABUTILON INDICUM LINN SWEET) ROOT WITH EQUAL QUANTITY OF SUGAR (SITA) AND COW MILK (GODUGDDHA) IN RELATION TO ANTI-DIABETIC ACTIVITY IN STREPTOZOTOCIN INDUCED ALBINO WISTAR RATS

Background: Diabetes mellitus, a clinical syndrome developed due to absolute or relative deficiency of insulin and it is mainly characterized by hyperglycemia. It has high prevalence and it is fast gaining status of potential epidemic. Thats why many synthetic drugs are available to treat the diabetes which is costly and giving serious side effects after long use. The herbs are safe and cost effective to treat diabetes. Ayurved classic (Bhavapraksh Nighantu) mentioned Atibala root with Sita (sugar) and Godugddha (Cow milk) have anti-diabetetic activity. As the Diabetes mellitus is most considerable disease by ethical issues hence it is decided to evaluate anti-diabetic activity of Atibala with sugar and cow milk in streptozotocin induced Albino Wistar rats. Aim and Objectives: To study Atibala root with equal quantity of sugar and cow milk as anti-diabetic activity. Methodology: In this study, 30 Albino Wistar rats will be divided randomly into 5 groups (6 in each). Test drugs will be administered for 21 days. The random blood glucose will be measured 0, 7, 14 & 21th days of drug administered. Anti-diabetic activity will be evaluated on biochemical parameter 0 day & at 21thday and on 22th day histopathological study of pancreas. Results: Changes will be observed in the objective outcomes. Conclusion: Atibala root with equal quantity of sugar and cow milk will have anti-diabetic activity.