STUDY OF PREVALENCE AND RISK FACTORS OF POLYCYSTIC OVARIAN SYNDROME AMONG ADOLESCENT AND YOUNG ADULTS OF RAMA UNIVERSITY

Background: There is little epidemiological data from India on the prevalence and risk factors associated with polycystic ovarian syndrome (PCOS). The objectives of the present study were to estimate the prevalence of PCOS using different criteria among adolescents and young women and to evaluate risk factors associated with PCOS. Materials and Methods: A total of 200 participants, adolescents (12-17 years, n = 100) and young women (18-30 years, n =100), were recruited. Participants who were overweight and having menstrual disorders or biochemical abnormalities were invited for ultrasonographic examination. A standardized questionnaire assessed the regularity of menstrual cycles, body hair growth, skin, body weight, sleep, and androgen excess. The ovarian volume and follicular size were assessed transabdominally. Prevalence of PCOS was assessed by the Rotterdam, AE-PCOS, and NIH criteria.Study period - 1st January 23 - 31st August 23 Results: The mean age of participants with PCOS was 21 ± 6.069 years and those without PCOS was 19.62±5.583 years. Mean body weight, body mass index, fasting insulin, systolic and diastolic blood pressures were significantly higher in the PCOS group. Prevalence of polycystic ovaries on ultrasonography was observed in 78.6% of the women with PCOS as against 5% in women without PCOS. Obesity (OR: 7.34, 95% CI: 1.95- 27.27), insulin resistance (OR:5.62, 95% CI :0.461 - 0.982) and hypertension (OR: 10.76, 95% CI: 0.916 - 0.998) were significantly associated with PCOS . Overall, the Prevalence of pcos was highest among female AGE GROUP 17-30YRS . Conclusion: There is a high prevalence of PCOS in today society, which emphasizes the need for urgent preventive and control measures. Early diagnosis and assessment of risk factor is therefore crucial in incorporating lifestyle and dietary modifications for weight reduction and better control of blood pressure at a younger age to further prevent long-term reproductive and metabolic disorders.