The Autoimmune Syndrome Through the Prism of Targeted AT-Mediated Proteolysis: Innovative Ideas, Philosophy, and Tools for Practitioners of The Next Step Generation |Biomedgrid
Journal: American Journal of Biomedical Science & Research (Vol.15, No. 3)Publication Date: 2022-01-18
Authors : Veronika Medvedeva; Eric James Sorenson; Mariya Studneva; Noel Rose; Aleks Gabibov; R Holland Cheng; Trevor G. Marshall; Philip D Cotter; Peter Virnau; Vassiliy Tsytsarev; Sofia Blokh; Sergey Suchkov;
Page : 321-329
Keywords : Catalytic Antibodies (abzymes); Antibody-proteases; Protabzymes; Biomarkers; per-sonalized and precision medicine;
Abstract
A feature of the modern laboratory-based personalized and precision diagnostics is a rapid intro-duction of the full-scale highly informative predictive and prognostic diagnostic technologies in-to the daily clinical practice. This trend is particularly evident in clinical immunology and biotechnology. The key link in the pathogenesis of autoimmune diseases is autoantibodies (auto-Abs), which have different levels of specificity and functionality, constituting the most important portion of a unified diagnostic strategy in the practice of an endocrinologist.
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